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Personal Information
	Name	Dorman, Charles James
	College Address	Microbiology, Moyne Institute
	Main Department	Microbiology
	College Title	Professor
	E-mail	cjdorman@tcd.ie
	College Tel	+353 1 896 2013/2521
	Web	http://people.tcd.ie/cjdorman
	Fax	00353 1 679 9294


Biography
Charles J Dorman holds the Chair of Microbiology at Trinity College Dublin. He is a Founding Member of the European Academy of Microbiology, a Fellow of the American Academy of Microbiology, a Member of the Royal Irish Academy, a Fellow of the Society of Biology and a Chartered Biologist. A recipient of the SGM Fleming Medal and a former Royal Society Research Fellow and Lecturer in Biochemistry at Dundee University, his research focuses on the global regulation of gene expression in bacteria of medical importance, with an emphasis on the regulatory roles of DNA topology and nucleoid-associated proteins.


Professional Qualifications

Qualification	Institution	Class of Degree	Title of Dissertation	Date Conferred
B.Sc. Microbiology	National University of Ireland, University College, Dublin	First Class		1981
Ph.D.	University of Dublin, Trinity College.			1985
M.A. (jure officii)	University of Dublin, Trinity College			1995
Sc.D.	University of Dublin, Trinity College			2005

Representations

Details	Date
Chair of Microbiology, Trinity College Dublin	Current
Head of the School of Genetics and Microbiology. Trinity College Dublin	2008-2011
Treasurer-elect, Society for General Microbiology	2011-2012
Member, Committee on Global Engagement, American Society for Microbiology	2012-2015
European Ambassador of the American Society for Microbiology	2010-2012
More Representations>>>


Administrative Functions

Details	Level	Date From	Date To
Chair of Microbiology, Trinity College Dublin	Chairman and Professor	Current
Head of School of Genetics and Microbiology	Head of School	2008	2011
European Ambassador for the American Society of Microbiology	Ambassador	2010	2012
Society for General MIcrobiology	Treasurer-elect	2011	2012
Director of Research, School of Genetics and Microbiology, Trinity College Dublin	Director	2005	2008
More Administrative Functions>>>

Membership of Professional Institutions, Associations, Societies

Details	Date From	Date To
European Academy of Microbiology (Founding Member)	Current
American Academy of Microbiology (Fellow)	Current
Royal Irish Academy (Member)	Current
Society of Biology (Fellow)	Current
Institute of Biology (Chartered Biologist)	Current
More Memberships>>>


Awards and Honours

Award	Date
Top performing editorial board member, Journal of Bacteriology (published by the American Society for Microbiology) http://jb.asm.org/content/195/1/1.full.pdf	2013
Outstanding Service Award, American Society for Microbiology International Ambassador Programme	2012
Elected Treasurer of the Society for General Microbiology	2011
Ambassador to Europe, American Society for Microbiology	2010-2012
Outstanding Service Award, American Society for Microbiology International Board	2011
More Awards and Honours>>>


Employment Details

Position Held	Job Description	Where	Date From	Date To
Postdoctoral Fellow		Biochemistry Department, University of Dundee, UK	1984	1988
Royal Society Research Fellow		Biochemistry Department, University of Dundee, UK	1988	1994
Lecturer		Biochemistry Department, University of Dundee, UK	1992	1994
Chair of Microbiology		University of Dublin, Trinity College	1994	Present

Description of Research Interests

1. Gene regulatory mechanisms in Gram-negative bacteria of medical importance, with an emphasis on the roles of nucleoid-associated proteins and DNA topology in controlling transcription and site-specific recombination. 2. Horizontal transfer of gene regulatory elements and the evolution of gene control networks. 3. The dissection and interpretation of complex gene regulatory circuits using genomics methods. 4. Modulation of gene expression patterns in pathogenic bacteria during infection and intracellular growth.


Research Interests

BACTERIA	BACTERIAL	BACTERIAL GENE	BACTERIUM
BINDING-PROTEINS	BINDING-SITE	BINDING-SITES	BIOCHEMICAL
BIOCHEMICAL APPROACH	BIOCHEMISTRY	BIOLOGY	CURVED DNA
DEOXYRIBONUCLEIC-ACID GYRASE	DNA	DNA ARRAY	DNA BENDING
DNA BINDING	DNA GYRASE	DNA INVERSION	DNA MICROARRAYS
DNA RECOGNITION DOMAINS	DNA SUPERCOILING	DNA SUPERHELICITY	DNA TOPOLOGY
DNA-BINDING	DNA-BINDING ACTIVITY	DNA-BINDING DOMAIN	DNA-BINDING DOMAINS
DNA-BINDING PROTEIN	DNA-BINDING PROTEINS	DNA-BINDING SUBUNIT	ENVIRONMENTAL REGULATION
ENVIRONMENTAL-REGULATION	ESCHERICHIA-COLI K-12	FIMBRIAE	FIMBRIAL PHASE VARIATION
FIS PROTEIN	GENE REARRANGEMENTS	GENE REGULATION	GENE-EXPRESSION
GENES	GENETIC	GENETIC MANIPULATION	GENETIC STRUCTURE
GENETIC-ANALYSIS	GENETICS	GENOME	GENOME COMPACTION
GENOME EVOLUTION	GENOME EXPRESSION ANALYSIS	GENOMES	GENOMIC ORGANIZATION
GENOMICS	GLOBAL REGULATOR	GROWTH-PHASE CONTROL	GROWTH-PHASE REGULATION
H-NS	HISTONE-LIKE PROTEINS	HNS	INTEGRATION HOST FACTOR
MESSENGER-RNA	MICROARRAY	MICROARRAY DATA	MICROBIAL ACTIVITY
MICROBIOLOGY	MICROORGANISM	MICROORGANISMS	MOLECULAR-BIOLOGY
MOLECULAR-CLONING	MOLECULAR-GENETICS	MOLECULAR-STRUCTURE	SALMONELLA-TYPHIMURIUM
SHIGELLA-FLEXNERI	SITE-SPECIFIC RECOMBINASES	TRANSCRIPTIONAL ACTIVATION	TYPE-1 FIMBRIAE

Publications and Other Research Outputs

Peer Reviewed

Organization of the Bacterial Nucleoid (Chapter 311) in, Lennarz W, Lane MD , Encyclopedia of Biological Chemistry (2nd Edition), Waltham, MA, USA, Academic Press, 2013, pp367 - 370, [Dorman CJ] Url
H-NS, global regulator of gene expression and organizer of the bacterial nucleoid in, A. Filloux , Bacterial Regulatory Networks, Norwich, Horizon Press, 2012, pp167 - 189, [CJ Dorman] Url
Kröger C, SC Dillon, ADS Cameron, K Papenfort, SK Sivasankaran, K Hokamp, Y Chao, A Sittka, M Hébrard, K Händler, A Colgan, P Leekitcharoenphon, GC Langridge, AJ Lohan, B Loftus, S Lucchini, DW Ussery, CJ Dorman, N Thomson, J Vogel, JCD Hinton, The transcriptional landscape and small RNAs of Salmonella enterica serovar Typhimurium, Proceedings of the National Academy of Science USA , 109, (20), 2012, pE1277 - E1286 Notes: [Published online 25 April 2012] DOI
Dillon SC, E Espinosa, K Hokamp, DW Ussery, J Casadesus, CJ Dorman, LeuO is a global regulator of gene expression in Salmonella enterica serovar Typhimurium, Molecular Microbiology, 85, (6), 2012, p1072 - 1089 Notes: [Published online 16 July 2012] DOI
McFarland KA, Dorman CJ, Autoregulated expression of the gene coding for the leucine-responsive protein, Lrp, in Salmonella enterica serovar Typhimurium , Microbiology, 154, (7), 2008, p2008 - 2016 DOI
More Publications and Other Research Outputs >>>

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